Mood Sense

Mood Sense is the only at-home test that empowers you to steady your mood. From start to finish, it takes 15 minutes to reveal what supplements and dosage will help you reduce the emotional noise and take back control.

How it will help you

Because Mood Sense is based in the metabolic science (1C Metabolics, methylation) that affects all human brains and bodies, it can help in varied situations:

  • Daily mood disruptions, like emotional supersensitivity, excessive rumination, persistent anger, worry, anxious and on edge, long-lasting sadness

  • Heightened emotions around menstrual cycles

  • Wild emotional fluctuations during menopause (perimenopause)

  • Emotionally meeting in the middle with your significant other

(At a fundamental level, it helps you to see and balance your methylation level.)

You can now feel better in 15 minutes!

Getting started

We don’t offer supplements (yet!), but we link you to a clean brand that works well.

It’s an easy saliva test

If you’ve taken a COVID test, you can do this easily.

  1. Brush teeth and tongue using water

  2. Lightly chew on a cotton swab to capture your saliva

  3. Extract and drop your saliva onto the test device

  4. After 15 minutes, record your results in the portal and get supplement dose recommendations (after you establish your “mood baseline”)

The Science

Mood Sense centers on 1C metabolic science, specifically your body’s current “methylation level”, or methyl supply. Your methyl supply determines how your genes are expressed: too little or too much results in genetic instructions being activated or suppressed at the wrong times.

We use the Methyl Scale™ to quantify your methyl supply. Based on your test result, the scale can help you determine the severity of methylation-based mood disruption that fluctuates based on hormones, diet, activity, illness and more.

How does methyl supply affect mood?

As your methyl supply changes, it changes how the genes responsible for creating your happy, focus, motivation, sleep, and control chemicals are expressed. This means that it creates and uses too much of a good thing (overmethylation), or not enough (undermethylation). These monoamine neurotransmitters (serotonin, dopamine, melatonin, norepinephrine, and epinephrine) are crucial for mood, sleep, memory, motivation, attention, and more.

When hormones fluctuate, it affects methylation which changes how quickly these neurotransmitters are recycled. This is another crucial aspect of mood. When neurotransmitters aren’t recycled properly, it can contribute to depression, anxiety, insomnia, agitation, decreased attention and motivation, and fatigue, among other symptoms.

How methylation manages mood

The monoamine neurotransmitters involved in this pathway include:

  • Serotonin. Mood regulation, happiness, appetite, sleep, social.

  • Melatonin. Sleep-wake and seasonal biological rhythms, regulate immune response (inflammation), menstrual cycle and fertility, neuro-protection.

  • Dopamine. Reward, pleasure, motivation, motor control, attention, learning, memory.

  • Norepinephrine. Attention, focus, stress response, mood regulation, heart rate and blood pressure.

  • Epinephrine. Acute stress response, heart rate, blood flow, mobilize energy for immediate use.

There are some important genes involved in 1C metabolism and methylation as well. The MTHFR, MTRR, and COMT genes (among others) have an impact on methylation levels and the methyl score, but they aren’t the only factors. Biological maturity (childhood, adolescence, adulthood, and post-menopause for females), sex at birth and associated hormones, detox genes, and your immune system all impact your methylation level.

From day-to-day—and even minute-to-minute—your diet, activity, illness, monthly cycle, menopause, stress levels, and detox status are changing your methyl supply. This is why Mood Sense is so important: you can track and address imbalances in minutes.